ISPP 2022
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Associate Professor Michael Jankowski
PhD
Theodore W Striker MD, Chair in Anesthesia Research, Associate Professor of Anesthesia and Pediatrics, Cincinnati Children's Hospital Medical Center, Ohio, USA
​Dr. Jankowski is the Theodore W. Striker, MD Endowed Chair in Anesthesia and Associate Professor of Anesthesia and Pediatrics at Cincinnati Children’s Hospital Medical Center (CCHMC).  He is a renowned sensory neuron biologist that joined the faculty at CCHMC in 2011. He has received numerous NIH, Department of Defense, foundation and institutional awards to support his research on mechanisms of nociceptive processing.  He is an Associate Editor for Pain and Molecular Pain and has served as an ad hoc reviewer for over 30 other peer reviewed journals. He has served on several US federal and foundation study sections and is an active mentor having trained over 20 individuals in the neurosciences.  He is currently the Director of Research in the Department of Anesthesia at CCHMC. He is also the Associate Director of Basic Science Research for the Center for Understanding Pediatric Pain (CUPP).
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Translating Basic Mechanisms of Pediatric Pain

Approximately 15-20% of children experience persistent or chronic pain. However, compared to adults, we know relatively little about the mechanisms of pediatric pain development. A basic understanding of nociceptive processing in the immature nervous system is therefore crucial in order to develop more appropriate treatments for pain in children.  Recent data indicates that the developing peripheral nervous system uniquely responds to tissue injury relative to older animals.  Interestingly, similar patterns of peripheral sensitization are observed in animals models of growth hormone deficiency (GHD) in which peripheral sensitization is observed specifically in neonates.  This is also observed in some patient populations with GHD-related disorders.  We further found that peripheral insult in neonates induces a target specific reduction in tissue GH levels that modulated injury-related responsiveness and appeared to be mediated by infiltrating macrophages.  This session will highlight the changing properties of developing sensory neurons and how the GH pathway may be a unique player in neonatal sensitization.  Attending professionals will be able to maintain an up to date knowledge of innovative advances in the pediatric pain field in addition to obtaining novel information about how preclinical research findings may translate into better clinical outcomes or original therapies for pediatric pain.
The 13th International Symposium on Pediatric Pain is proudly brought to you by
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The 13th International Symposium on Pediatric Pain is generously supported by:
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